Publications

2026

  1. Molecular Glue-like Degraders of TEM β-Lactamases by Periplasmic Protease DegP
    Emilia Taylor, Patricia Santos Barbosa, Tarini Kadambi, Frederik Eisele, Elisabete C. C. M. Moura, Timothy Walsh, Georgia Isom, and Thomas Lanyon-Hogg
    bioRxiv, 2026.
    PDF
  2. YdbL directly modulates YdbH-YnbE bridge formation to maintain Escherichia coli outer membrane homeostasis
    Clare DeAth, Sujeet Kumar, Sachi Chhibber, Benjamin Cooper, Emilia Taylor, Emily Jones, Thomas Lanyon-Hogg, Jani Bolla, Christina Redfield, Natividad Ruiz, and Georgia Isom
    bioRxiv, 2026.
    PDF

2025

  1. Live-Cell Chemoproteomic Profiling Identifies the Uncharacterised Protein YbaA as a Direct Target of Ciprofloxacin in Escherichia coli
    Tricia seow, Jacob Bradbury, Emilia Taylor, Ludwig Bauer, Madja Harvey, Yiqiao Wang, Adam Thomas, Patricia Santos Barbosa, Kilian Huber, Georgia Isom, and Thomas Lanyon-Hogg
    bioRxiv, 2025.
    PDF

2024

  1. PROTAC2.png
    Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance
    Jacob D Bradbury, Thomas Hodgkinson, Adam M Thomas, Omprakash Tanwar, Gabriele La Monica, Vanessa V Rogga, Luke J Mackay, Emilia K Taylor, Kiera Gilbert, Yihua Zhu, and  others
    Chemical Science, 2024.
    PDF

2023

  1. PROTAC1.png
    Rapid PROTAC discovery platform: nanomole-scale array synthesis and direct screening of reaction mixtures
    Mateusz P Plesniak, Emilia K Taylor, Frederik Eisele, Christopher MBK Kourra, Iacovos N Michaelides, Alice Oram, Johan Wernevik, Zulma Santisteban Valencia, Hannah Rowbottom, Nadia Mann, and  others
    ACS medicinal chemistry letters, 2023.
    PDF